I. Personal information

Title: Professor

Highest academic degree: Ph.D

E-mail: dczhucn@ujs.edu.cn

II. Academic background

Professor/Researcher, School of the Environment and Safety Engineering, Jiangsu University, 2009-Present

Visiting Scholar, Washington State University, USA, Biological Systems Engineering, 2014/02–2014/9

Ph.D. in Environmental Biochemistry, Kobe University, 2004-2008

M.S. in Fermentation Engineering, Dalian Polytechnic University, 2001-2004

B.S. in Food Science, Qilu University of Technology, 1996-2000

III. Research fields

Synthetic Biology, Exploitation of Novel Environmental Microorganism and Enzyme Resources, Marine Environmental Ecology, Bio-degradation of Organic Pollutants, Biomass Conversion and Lignin Valorization

IV. Key scientific research projects

Prof. Zhu Daochen headed/heading more than 10 natural science foundation projects.  Key scientific research projects in recent years are as follows:

1. The key technologies for biotransformation of natural vanillin from lignin biodepolymerization（The National Key Research and Development Program of Jiangsu Province, supported by Jiangsu Provincial Department of science and technology, China, 2021-2024）

2. Processing biomimetic technologies for converting lignocellulose into high-value added consumer and industrial products (The National Key Research and Development Program of China , supported by Ministry of science and technology of China, 2019–2023)

3. Analysis and regulation of multiple reverse electron transport pathways in microbial electroreduction of heavy metal pollutants (supported by National Natural Science Foundation of China, 2016–2019）

4. Efficient synthesis and production of ectoine by marine microorganisms (supported by Science and Technology Department of Jiangsu, China, 2013–2016)

5. The study on the mechanism of regulation and trigger of the synthesis metabolism pathway of hydroxyectoine in halotolerant bacterium in response to extreme environment (supported by Science and Technology Department of Jiangsu, China, 2012-2015)

6. The synthesis and excretion of hydroxyectoine in halophilic bacteria. (supported by Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, 2012-2015)

V. Main achievements

Prof. Zhu Daochen has published more than 40 significant scientific papers in reputational journal, four book chapter and as editor published one book.

Research papers:

1. Li, Y., Qaria, M.A., Sethupathy, S., Sun, J., & Zhu, D^*.  (2021). Curcumin production and bioavailability: A comprehensive review of curcumin extraction, synthesis, biotransformation and delivery systems. Industrial Crops and Products, 172, 114050.

2. Sethupathy, S., Morales, G. M., Li, Y., Wang, Y., Jiang, J., Sun, J., & Zhu, D^*. (2021). Harnessing microbial wealth for lignocellulose biomass valorization through secretomics: a review. Biotechnology for Biofuels, 14(1), 1-31.

3. Fiaz, A., Zhu, D^*., & Sun, J^*. (2021). Environmental fate of tetracycline antibiotics: degradation pathway mechanisms, challenges, and perspectives. Environmental Sciences Europe, 33(1), 1-17.

4. Xu, L.; Sun, J.; Qaria, M.A.; Gao, L.; Zhu, D^*. (2021). Dye Decoloring Peroxidase Structure, Catalytic Properties and Applications: Current Advancement and Futurity. Catalysts, 11,955. https://doi.org/10.3390/catal11080955

5. Ali, S. S., Elsamahy, T., Al-Tohamy, R., Zhu, D., Mahmoud, Y., Koutra, E., ... & Sun, J. (2021). Plastic wastes biodegradation: mechanisms, challenges and future prospects. Science of The Total Environment, 146590.

6. Geng, A., Jin, M., Li, N., Zhu, D., Xie, R., Wang, Q., ... & Sun, J. (2021). New Insights into the Co-Occurrences of Glycoside Hydrolase Genes among Prokaryotic Genomes through Network Analysis. Microorganisms, 9(2), 427.

7. Ali, S. S., Elsamahy, T., Koutra, E., Kornaros, M., El-Sheekh, M., Abdelkarim, E., Zhu, D., & Sun, J. (2021). Degradation of conventional plastic wastes in the environment. A review on current status of knowledge and future perspectives of disposal. Science of the Total Environment, 144719.

8. Zhu, D^*., Liang, N., Zhang, R., Ahmad, F., Zhang, W., Yang, B., ... & Sun, J^*. (2020). Insight into depolymerization mechanism of bacterial Laccase for lignin. ACS Sustainable Chemistry & Engineering, 8(34), 12920-12933.

9. Zhu, D^*., Adebisi, W. A., Ahmad, F., Sethupathy, S., Danso, B., & Sun, J^*. (2020). Recent development of extremophilic bacteria and their application in biorefinery. Frontiers in Bioengineering and Biotechnology, 8, 483.

10. Ahmad, F., Zhu, D^*., & Sun, J. (2020). Bacterial chemotaxis: a way forward to aromatic compounds biodegradation. Environmental Sciences Europe, 32(1), 1-18.

11. Morales, G. M., Ali, S. S., Si, H., Zhang, W., Zhang, R., Hosseini, K., ... & Zhu, D^*. (2020). Acidic Versus Alkaline Bacterial Degradation of Lignin Through Engineered Strain E. coli BL21 (Lacc): Exploring the Differences in Chemical Structure, Morphology, and Degradation Products. Frontiers in bioengineering and biotechnology, 8, 671.

12. Wu, J., Tao, Y., Geng, A., Xie, R., Zhu, D., Wang, Q., ... & Sun, J. (2020). Acetylation of bacterial cellulose using N-methyl-imidazole as a catalyst under solvent-free and N, N-dimethylacetamide/lithium chloride solvent systems. BioResources, 15(2), 3688.

13. Li, F., Xie, R., Liang, N., Sun, J., & Zhu, D^*. (2019). Biodegradation of lignin via Pseudocitrobacter anthropi MP-4 isolated from the gut of wood-feeding termite Microtermes pakistanicus (Isoptera: Termitidae). BioResources, 14(1), 1992-2012.

14. Li, Y., Zhu, X., Zhang, W^*., Zhu, D^*., Zhou, X., & Zhang, ^*L. (2019). Archaeal communities in the deep-sea sediments of the South China Sea revealed by Illumina high-throughput sequencing. Annals of Microbiology, 69(8), 839-848.

15. Zhu, D^*., Si, H., Zhang, P., Geng, A., Zhang, W., Yang, B., ... & Sun, J^*. (2018). Genomics and biochemistry investigation on the metabolic pathway of milled wood and alkali lignin-derived aromatic metabolites of Comamonas serinivorans SP-35. Biotechnology for biofuels, 11(1), 1-15.

16. Geng, A., Cheng, Y., Wang, Y., Zhu, D., Le, Y., Wu, J., ... & Sun, J. (2018). Transcriptome analysis of the digestive system of a wood-feeding termite (Coptotermes formosanus) revealed a unique mechanism for effective biomass degradation. Biotechnology for biofuels, 11(1), 1-14.

17. Zhu, D^*., Zhang, P., Xie, C., Zhang, W., Sun, J., Qian, W. J., & Yang, B^*. (2017). Biodegradation of alkaline lignin by Bacillus ligniniphilus L1. Biotechnology for biofuels, 10(1), 1-14.

18. Zhang, P. P., Sun, J. Z., Xie, C. X., & Zhu, D. C^*. (2017). Lignin degradation by Comamonas serinivorans C35. Microbiol China, 44, 1131-1137.

19. Zhu, D., Zhang, P., Niu, L., Xie, C., Li, P., Sun, J., & Hang, F. (2016). Bacillus ectoiniformans sp. nov., a halotolerant bacterium isolated from deep-sea sediments. International journal of systematic and evolutionary microbiology, 66(2), 616-622.

20. Zhu, D^*., Zhang, P., Li, P., Wu, J., Xie, C., Sun, J., & Niu, L. (2016). Description of Leucobacter holotrichiae sp. nov., isolated from the gut of Holotrichia oblita larvae. International journal of systematic and evolutionary microbiology, 66(4), 1857-1861.

21. Qiu, H., Geng, A., Zhu, D., Le, Y., Wu, J., Chow, N., ... & Sun, J. (2015). Purification and characterization of a hemocyanin (Hemo1) with potential lignin-modification activities from the wood-feeding termite, Coptotermes formosanus Shiraki. Applied biochemistry and biotechnology, 175(2), 687-697.

22. Niu, L., Xiong, M., Zhu, D., Song, L., Tang, T., & Li, W. (2016). Pullulanibacillus camelliae sp. nov., isolated from Pu’er tea. International journal of systematic and evolutionary microbiology, 66(11), 4760-4765.

23. Niu, L., Tang, T., Song, L., Xiong, M., Tian, J., Zhang, K., ... & Zhu, D^*. (2015). Pullulanibacillus pueri sp. nov., isolated from Pu'er tea. International journal of systematic and evolutionary microbiology, 65(Pt_7), 2167-2171.

24. Zhu, D., Tanabe, S. H., Xie, C., Honda, D., Sun, J., & Ai, L^*. (2014). Bacillus ligniniphilus sp. nov., an alkaliphilic and halotolerant bacterium isolated from sediments of the South China Sea. International journal of systematic and evolutionary microbiology, 64(Pt_5), 1712-1717.

25. Zhu, D^*., Xie, C., Huang, Y., Sun, J., & Zhang, W. (2014). Description of Comamonas serinivorans sp. nov., isolated from wheat straw compost. International journal of systematic and evolutionary microbiology, 64(Pt_12), 4141-4146.

26. Chen, T., Wu, Q., Li, S., Xiong, S., Jiang, S., Tan, Q., Zhu, D^*., & Wei, H^*. (2014). Microbiological quality and characteristics of probiotic products in China. Journal of the Science of Food and Agriculture, 94(1), 131-138.

27. Zhu, D^*., Tanabe, S. H., Yang, C., Zhang, W., & Sun, J. (2013). Bacterial community composition of South China Sea sediments through pyrosequencing-based analysis of 16S rRNA genes. PloS one, 8(10), e78501.

28. Liu, X., Zhu, D., Sun, L., Gao, Y., & Wang, C. (2013). Effect of L-arabinose on the postprandial blood glucose and body weight. Wei sheng yan jiu= Journal of hygiene research, 42(2), 295-297.

29. Zhu, D^*., Li, P., Tanabe, S. H., & Sun, J^*. (2013). Genome sequence of the alkaliphilic bacterial strain Bacillus ligninesis L1, a novel degrader of lignin. Genome announcements, 1(2), e00042-13.

30. Chen, T., Jiang, S., Xiong, S., Wang, M., Zhu, D^*., & Wei, H. (2012). Application of denaturing gradient gel electrophoresis to microbial diversity analysis in Chinese Douchi. Journal of the Science of Food and Agriculture, 92(10), 2171-2176.

31. Zhu, D^*., Wang, C., Hosoi-Tanabe, S., Zhang, W., & Nagata, S. (2011). The synthesis and role of hydroxyectoine in halophilic bacterium Halomonas ventosae DL7. African Journal of Microbiology Research, 5(16), 2254-2260.

32. Chen, T., Wang, M., Jiang, S., Xiong, S., Zhu, D^*., & Wei, H. (2011). Investigation of the microbial changes during koji‐making process of Douchi by culture‐dependent techniques and PCR‐DGGE. International Journal of Food Science & Technology, 46(9), 1878-1883.

33. Zhu, D., Cui, S., & Nagata, S. (2008). Isolation and characterization of salt-sensitive mutants of the moderately halophilic bacterium Salinivibrio costicola subsp. yaniae. Bioscience, biotechnology, and biochemistry, 72(8), 1977-1982.

34. Zhu, D., Zhang, W., Zhang, Q., & Nagata, S. (2010). Accumulation and role of compatible solutes in fast-growing Salinivibrio costicola subsp. yaniae. Canadian journal of microbiology, 56(12), 1020-1027.

35. Hosoi-Tanabe, S., Zhang, H., Zhu, D., Nagata, S., Ban, S., & Imura, S. (2010). Comprehensive analysis of an Antarctic bacterial community with the adaptability of growth at higher temperatures than those in Antarctica. Biocontrol science, 15(2), 57-62.

36. Zhu, D., Miyake, H., & Nagata, S. (2008, April). Role of Compatible Solutes in the Fast Growth Bacterium Salinivibrio costicola subsp. yaniae. In OCEANS 2008-MTS/IEEE Kobe Techno-Ocean (pp. 1-4). IEEE.

37. Zhu, D., Osman, O., & Nagata, S. (2008, April). Physiological role of compatible solute hydroxyectoine, synthesized in the halophilic Halomonas ventosae DL7. In OCEANS 2008-MTS/IEEE Kobe Techno-Ocean (pp. 1-3). IEEE.

38. Zhu, D., Cui, S., Wei, J., & Nagata, S. (2007, October). Isolation and Characterization of Salt-sensitive Mutants of the Moderately Halophilic Bacterium, Salinivibrio sp. DL6. In 2007 Frontiers in the Convergence of Bioscience and Information Technologies (pp. 21-25). IEEE.

39. Zhu, D., Niu, L., Wang, C., & Nagata, S^*. (2007). Isolation and characterisation of moderately halophilic bacterium Halomonas ventosae DL7 synthesizing ectoine as compatible solute. Annals of microbiology, 57(3), 401-406.

40. Zhang, L., Wang, Y., Zhang, C., Wang, Y., Zhu, D., Wang, C., & Nagata, S^*. (2006). Supplementation effect of ectoine on thermostability of phytase. Journal of bioscience and bioengineering, 102(6), 560-563.

41. Wang, C., Zhu, D., & Nagata, S^*. (2006). Supplementation effects of hydroxyectoine on proline uptake of downshocked Brevibacterium sp. JCM 6894. Journal of bioscience and bioengineering, 101(2), 178-184.

42. Zhang, L., Zhao, C., Zhu, D., Ohta, Y., & Wang, Y^*. (2004). Purification and characterization of inulinase from Aspergillus niger AF10 expressed in Pichia pastoris. Protein expression and purification, 35(2), 272-275.

Editors/Guest Editors service

1. Shahnawaz, M., Sangale, M.K., Daochen, Z., Ade, A.B. (2021) Impact of Plastic Waste on the Marine Biota (Eds.)  Springer Nature Singapore Pte Ltd. DOI10.1007/978-981-16-5403-9

2. Guest Associate Editor, Frontiers in Bioengineering and Biotechnology, the topic: Lignin Valorization: Recent Trends and Future Perspective