方真,副教授(87978797威尼斯老品牌副研究员),硕士生导师
教育背景
2016年,美国伦斯勒理工大学生物技术和跨学科研究中心访问学者;
2011.09至2016.12,江南大学,发酵工程(轻工技术与工程,国家双一流学科),博士学位;
2008.09至2011.09,江南大学,生物工程,学士学位。
研究方向
高催化活性生物元件的挖掘与理性设计研究;
附加值化合物的合成生物学设计和代谢工程研究;
光/电驱动微生物的能量转换机制及其固碳/固氮研究。
主持项目
1. 国家重点研发计划重点专项(高能糖电池设计与构建,子课题“酶元件基因的精准挖掘和高通量筛选”负责人,2022)
2. 87978797威尼斯老品牌农业装备学部项目(养殖水体生物毒性原位实时预警的自供能关键传感装置研发,2022,20万)
3. 国家自然科学基金青年基金(电驱动希瓦氏菌固碳的NADH再生机制和调控研究, 2020)
4. 江苏省自然科学基金青年项目(希瓦氏菌复合导电网络构建及贵金属生物还原机制研究,2019)
参与项目:
1. 内蒙古自治区科技重大专项(低成本煤化工CO2捕集与压缩技术开发与示范,2021SZD0087,3000万,参与,2021)
2. 国家自然科学基金面上项目(基于原位超分辨技术的微生物胞外电子传递终端协作机制研究,59万,3/5,2019)
3. 江苏省科技厅产学研项目(葡萄糖氧化酶高效酶制剂制备及应用关键技术,100万,2/10,2016)
4. 江苏省自然科学基金青年项目(外源极耐热性酶的表达对能源植物生物质降解的影响,3/5,2014)
荣誉/称号
1. 江苏省科技副总(2022)
2. 87978797威尼斯老品牌“青年英才培育计划”(2022)
3. 江苏省百篇优秀博士论文(2018)
4. 国家人社部/博管办博士后创新人才“博新计划”获得者(新型节能生物杂合体系的光驱动高效固氮研究,2018,60万,87978797威尼斯老品牌第一位获奖者)
主要论文
长期致力于环境微生物、环境工程、生物化工相关的研究。近五年,在Nat. Commun., Curr. Opin. Biotech., Adv. Energy Mat., Environ. Total Sci., ACS Sustainable Chem. Eng., Chem. Eng. J., AIChE J., Appl. Microbiol. Biotechnol., Biosens. Bioelectron., Biotechnol. J., Microb. Biotechol.等国际期刊上发表SCI论文25篇,其中影响因子10.0以上6篇,h指数15;担任Biotechnol. Adv., Front Microbiol., Bioresource Tech., Energy Convers. Manage., Chem Eng, J.等主要学术期刊的客座编辑或审稿人。
5篇代表性论文如下:
1. Han Chen; Yu Huang; Chong Sha; Jamile Mohammadi Moradian; Yong-Chun Yong; Zhen Fang*. Enzymatic carbon dioxide to formate: Mechanisms, challenges and opportunities. Renewable and Sustainable Energy Reviews, 2023, 178: 113271. (中科院一区,IF= 15.9)
2. Han Chen, Jiawei Li, Qichao Fan, Tao Zheng, Yafei Zhang, Yong-Chun Yong; Zhen Fang*. A feasible strategy for microbial electrocatalytic CO2 reduction via whole-cell-packed and exogenous-mediator-free rGO/Shewanella biohydrogel. Chemical Engineering Journal, 2023, 460: 141863. (中科院一区,IF= 15.1)
3. Zhen Fang, Yinjie J Tang, Mattheos AG Koffas. Harnessing electrical-to-biochemical conversion for microbial synthesis, Current Opinion in Biotechnology, 2022, 75, 102687. (中科院一区)
4. Zhen Fang, Jun Zhou, Xiangtong Zhou, Mattheos AG Koffas. Abiotic-biotic hybrid for CO2 biomethanation: From electrochemical to photochemical process. Science of the Total Environment, 2021, 79, 1148288. (中科院一区)
5. Di Suo, Zhen Fang*, Yang-Yang Yu, Yong-Chun Yong. Synthetic curli enables efficient microbial electrocatalysis with stainless-steel electrode. AIChE Journal, 2020, e16897.
其他论著:
1. Su N., Zhu D., …, Fang Z., Zhou X., Li C., (2022) Dong H. 3D/2D Heterojunction Fabricated from RuS2 Nanospheres Encapsulated in Polymeric Carbon Nitride Nanosheets for Selective Photocatalytic CO2 Reduction to CO. Inorganic Chemistry, 61, 15600–15606. (Nature Index期刊)
2. Ma L.#,Fang Z.#, Wang Y.Z., Zhou J., Yong Y. C. (2020) Photo-driven highly efficient one-step CO2biomethanation with engineered photo-synthetic bacteriaRhodopseudomonas palustris. ACS Sustainable Chemistry & Engineering, 2020,8, 9616-9621.
3. Bifu Luo, Yan-Zhai Wang, Di Li, Hongqiang Shen, Li-Xia Xu, Zhen Fang, Zhenglong Xia, Jianlin Ren, Weidong Shi, Yang-Chun Yong. A Periplasmic Photosensitized Biohybrid System for Solar Hydrogen Production. Advanced Energy Materials, 2021, 2100256. (中科院一区,IF=29.698)
4. Yang-Yang Yu, Yan-Zhai Wang, Zhen Fang, Yu-Tong Shi, Qian-Wen Cheng, Yu-Xuan Chen, Weidong Shi, Yang-Chun Yong, Single cell electron collectors for highly efficient wiring-up electronic abiotic/biotic interfaces, Nature Communications, 2020, 11, 4087. (Nature系列子刊, IF= 17.694)
5. Naraginti, S., Yu, Y.Y., Fang, Z., Yong, Y.C. (2019) Novel tetrahedral Ag3PO4@N-rGO for photocatalytic detoxification of sulfamethoxazole: Process optimization, transformation pathways and biotoxicity assessment. Chemical Engineering Journal, 375, 122035 (化工领域Top期刊)
6. Jamile Mohammadi Moradian, Xu Z. A., Shi Y. T., Fang Z., Yong Y. C. (2020) Efficient biohydrogen and bioelectricity production from xylose by microbial fuel cell with newly isolated yeast ofCystobasidium slooffiae. International Journal of Energy Research, 44, 325-333.
7. Zhai D.D.#, Fang Z.#, JIn H., Hui M., Kirubaharan C.J., Yu Y.Y., Yong Y. C. (2019) Vertical Alignment of Polyaniline Nanofibers on Electrode Surface for High-Performance Microbial Fuel Cells. Bioresource Technology, 288, 121499. (能源与燃料领域Top期刊)
8.Fang Z., Sha C., Peng Z., Zhang J., Du G.C. (2019) Protein engineering to enhance keratinolytic protease activity and excretion in Escherichia coli and its scale-up fermentation for high extracellular yield.Enzyme and Microbial Technology, 121, 37-44. (酶催化工程领域内知名期刊)
9.Fang, Z., Jones, J. A., Zhou, J., & Koffas, M. A. (2018). Engineering Escherichia coli Co‐Cultures for Production of Curcuminoids From Glucose. Biotechnology Journal, 13(5), 1700576.(合成生物学知名期刊,杂志当月封面文章)
10. Yang, Y., Yu, Y. Y., Wang, Y. Z., Zhang, C. L., Wang, J. X.,Fang, Z., ... & Yong, Y. C. (2017). Amplification of electrochemical signal by a whole-cell redox reactivation module for ultrasensitive detection of pyocyanin. Biosensors and Bioelectronics, 98, 338-344. (生物电化学领域Top期刊)
专利
(1) 雍阳春, 索迪, 方真。表达功能化淀粉样纤维的希瓦氏菌及其构建方法与应用。2020.05.20,202010430308.5
(2) 周到, 雍阳春, 方真。一种具备石墨烯亲和能力的希瓦氏菌及其构建方法与应用。2020.12.30,202011624040.5
(3) 雍阳春, 周到, 方真。一种生物素化Curli蛋白的活细胞标记方法及其应用。2020.12.30,202011624004.9
(4) 雍阳春, 刘想, 俞洋洋, 方真。一种聚苯胺纳米花修饰的碳布电极及其制备方法和用途。2017.09.25,201710875837.4
竞赛获奖
1. 2023_87978797威尼斯老品牌节能减排社会实践与科技竞赛_一等奖_0123 (本科生组)
2. 2023_87978797威尼斯老品牌节能减排社会实践与科技竞赛_二等奖_0042 (研究生组)
3. 2022全国大学生生命科学探究类三等奖
联系方式
江苏省镇江市学府路301号,87978797威尼斯老品牌生物质能源研究院,304室
Email:zhenfang@ujs.edu.cn; zhenfang89@hotmail.com